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[Crit Care Med在线发表]：基于人口的全身性感染流行病学：中国数据
2017年05月16日 ⁄ 时讯速递,
Population-Based Epidemiology of Sepsis in a Subdistrict of Beijing
Jianfang Zhou, Hongcheng Tian, Xueping Du, et al.
Crit Care Med. 2017 Apr 18.
doi: 10.1097/CCM.0000000000002414. [Epub ahead of print]
下载请点击此处Population-Based Epidemiology of Sepsis in a Subdistrict of Beijing
Objective: 研究目的
Information about the epidemiology of sepsis in community residents in China remains scarce and incomplete. The purpose of this study was to describe the occurrence rate and outcome of sepsis in Yuetan Subdistrict of Beijing and to estimate the occurrence rate of sepsis in China.
目前关于中国大陆社区居民全身性感染发病情况的研究很少，相关信息尚不完善。本研究的目的是了解北京市西城区月坛街道全身性感染的发病率以及患者预后，并以此推测中国大陆全身性感染的发病情况。
Design: 研究设计
Retrospective cohort study.
回顾性队列研究。
Setting: 研究场所
All public hospitals serving residents in Yuetan Subdistrict, Beijing.
月坛街道居民在研究期间入住过的北京公立医院。
Patients: 研究对象
All patients (n = 1,716) meeting criteria for sepsis based on American College of Chest Physicians/Society of Critical Care Medicine consensus definition.
根据美国胸科医师学会/ 危重病医学会共识中的相关定义，所有符合全身性感染诊断标准的患者（n=1716）均纳入研究。
Interventions: 干预措施
None.
无。
Measurement and Main Results: 研究结果
We screened all adult residents in Yuetan Subdistrict who were hospitalized from July 1, 2012, to June 30, 2014, and reviewed medical records. Patients with sepsis were included in the analysis. We enrolled 1,716 patients with sepsis out of 21,191 hospitalized adults screened, among whom severe sepsis developed in 256 patients, and septic shock developed in 233 patients. The crude annual occurrence rates of sepsis, severe sepsis, and septic shock in Yuetan Subdistrict were 667, 103, and 91 cases per 100,000 population, corresponding to standardized occurrence rates of 461, 68, and 52 cases per 100,000 population per year, respectively. Both occurrence rate and mortality increased significantly with age, although males had higher age-adjusted occurrence rate and mortality. The occurrence rate of sepsis also exhibited seasonal variation, peaking in winter season. The overall hospital mortality rate of sepsis was 20.6%, yielding a standardized mortality rate of 79 cases per 100,000 population per year.
首先，挑选出所有研究期间（2012.07.01~2014.06.30）入住过北京公立医院的月坛街道居民，然后查阅其病历，入院时或住院期间合并全身性感染的患者均纳入分析。结果显示，一共21191人住院，其中1716名患者符合全身性感染诊断标准，256名患者出现严重全身性感染，233名患者出现感染性休克。月坛街道全身性感染、严重全身性感染及感染性休克的发病率分别为667，103及91例/10万人/年；通过对年龄、性别进行校正，推测全国全身性感染、严重全身性感染及感染性休克的发病率分别为461，68及52例/10万人/年。随着年龄增加，全身性感染的发病率及病死率均呈上升趋势。男性全身性感染的发病率及病死率均高于女性。全身性感染的发病率与季节相关，冬季发病率最高。全身性感染住院病死率为20.6%，校正后推测全国全身性感染的病死率约79例/10万人/年。
Conclusions: 结论
Sepsis is a common and frequently fatal syndrome in Yuetan Subdistrict, Beijing. The occurrence rate and mortality of sepsis are significantly higher in males and elderly people.
北京月坛街道全身性感染的发病率及病死率均较高，男性及老年患者更高。
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发表于 2017-6-23 08:03:00
发表于 2017-6-23 08:03:01
