|
|
本帖最后由 细菌耐药 于 2017-2-1 02:55 编辑
Before my reseach, my boss give me three paper to learn, I share them with our SIFIC members.
Maybe we can disscussion them, if you are interested in these papers.
This is the second one.
Curr Opin Microbiol. 2015 Feb;23:23-31. doi: 10.1016/j.mib.2014.10.010. Epub 2014 Nov 11.
Salmonella enterica: living a double life in epithelial cells.
[size=13.9997px]Author information
Abstract[size=1.04em]Intracellular bacterial pathogens can occupy a membrane-bound vacuole or live freely within the cytosol of mammalian cells. Many studies have shown that the enteric bacterium, Salmonella enterica serovar Typhimurium (S. Typhimurium), is a vacuolar pathogen. Recent data, however, have revealed that within epithelial cells there are subpopulations of vacuolar and cytosolic Salmonella. Release from the Salmonella-containing vacuole leads to transcriptional reprogramming of bacteria and their robust replication in the cytosol. Eventually, epithelial cell death via pyroptosis results in cell lysis, proinflammatory cytokine release and escape of the cytosolic bacteria into the extracellular space, providing a potential mechanism of dissemination. This review focuses on the current understanding of this newly described intracellular population of Salmonella.[size=0.93em]Copyright © 2014 Elsevier Ltd. All rights reserved.
PMID: 25461569 DOI: 10.1016/j.mib.2014.10.010
Salmonella-containing vacuoles- directing traffic and nesting to grow_.pdf
2017-2-1 02:55 上传
点击文件名下载附件
下载积分: 金币 -2 金
560.45 KB, 下载次数: 12, 下载积分: 金币 -2 金
living, double, share
上一篇:Paper Share 1: Taking Possession Biogenesis the Salmonella-containing下一篇:paper share 3: The Samonella-containing vacuole-Moving with the times
|
|
发表于 2017-2-1 02:53:00
发表于 2017-2-1 02:53:01
